John Tweedale was born c. 1781 in Scotland.
He was entered in the Navy List of Medical Officers in 1814.
John Tweedale was employed as Surgeon Superintendent on the Coromandel to Van Diemen's Land in 1838. The Coromandel sailed from Sheerness 27 June 1838 and arrived on 25 October with cargo, 349 male prisoners and soldiers of the 51st and 21st regiment.
He was on the List of Surgeons of the Royal Navy who were unfit for service in 1841.
He can be found in the 1851 Census residing in King's Lynn. Age 70 years of age. Occupation Magistrate for Lynn, M.D. Aberdeen University on half pay as Surgeon, Royal Navy. His wife Harriet age 55 who was born in Middlesex resided with him. They had three servants.